Neurocysticercosis (NCC) is considered the most common helminth infection of the human nervous system and the most frequent preventable cause of epilepsy in sub-Saharan Africa. Since helminths have evolved co-evolutionary with mankind, they have developed multiple strategies to escape recognition by their hosts’ immune system resulting in a heterogeneous immune profile. An essential prerequisite to study the underlying immunological pathomechanisms that influence the development of symptomatic NCC is well-structured recruitment of patients with T. solium (neuro)cysticercosis/taeniosis (TSCT/NCC). In this proposal, a comprehensive field data collection in a highly endemic area of northern Mozambique for the calculation of prevalence proportions of TSCT/NCC (adults and children) will be complemented with clinical and immunological work-up.

The Department of Parasitology of Medical Faculty, of the Eduardo Mondlane University and the Mozambique Institute for Health Education and Research (MIHER), from Mozambique, members of this consortium, are the institutions which will take care of the research of the epidemiology of T. solium cysticercosis/taeniosis with special emphasis on neurocysticercosis and its related immunological pathomechanisms in northern Mozambique.

 

FUNCTION WITHIN CONSORTIUM

1. Provide data on human health, particularly prevalence of TSCT/NCC, pathomechanisms of NCC and treatment related data in immunocompetent subjects.

Emilia Virginia Noormahomed
Principal Investigator
Prof. Dr. Noormahomed is Full Professor of Human Parasitology at Universidade Eduardo Mondlane (UEM) in Maputo, Mozambique and invited Professor at the University of California San Diego (UCSD) in the United States of America. She is a humoral immunologist, whose research has focused on developingpoint of care diagnostic tools for T. solium and other infectious disease,as well as, the clinical and epidemiological aspects of those diseases, including the co infection with HIV. Another field of her research is related to medical education where she is dedicated at developing innovative strategies to scale up health professionals training and training the next generation of faculties and researchers with didactic and research skills in the country and through Africa. In CYSTINET-Africa project, Professor Noormahomed will serve as Principal Investigator and Coordinator of all Mozambique activities and will establish the linkage with other key internal and external stakeholders.
Iva Chirrime
Research Administrator
Iva Chirrime has her training in biological sciences. During her college, she worked at Simbiosis in Florianopolis-Brazil as a project manager involved in the coordination of social and environmental projects. Upon to return to Mozambique, she worked for IMPACTO as research assistant in a research project aimed to assess environmental impact in northern of Mozambique. Following this work, she shifted the focus to biomedical research when became research assistant at MIHER. Through her work at MIHER she began to develop an understanding of the challenges to research administration and the importance of effective collaboration with both domestic and international partners involved initially in projects focused in neglected diseases as Cysticercoses in Mozambique. For the CYSTINET-Africa project, she will be the research administrator and will be responsible to provide the compliance and management of the project.
Irene Alda Langa
Field Coordinator
Irene AldaLanga is a Veterinarian Medical Doctor and she also has Diploma on Applied Parasitology and Entomology. She is working as researcher and lecturer in Human Parasitology and at the Faculty of Medicine of Eduardo Mondlane University in Maputo, Mozambique since The Year of 2002. In research, She is most interested on Neglected Tropical Diseases. She has been working on lymphatic filariasis (LF) since 2002 where she was involved in mapping of the LF distribution, over the country as well as monitoring and evaluating the ongoing control program. She also worked as WHO temporary consultant on LF mapping and control programs in Portuguese speaking countries wish are endemic for these disease such as Angola and Guinea Bissau. In CYSTIENT-Africa (Mozambique), She will serve as field coordinator, coordinating all the activities and will be full-time based on the field (Mocuba).
Momade Amisse Ali
IT Task Force
Dr. Momade Amisse Ali is Master in Information Science and Assistant Lecturer at Universidade Lúrio since 2008, in field of Social Sciences and Health Information Systems. Since 2011 he is head of Documentation Services supporting Libraries and Information services at University. In terms of research he is involved on Doctoral Program in Education Science, specializing in innovative education at Universidade Católica de Moçambique, in research line of new ICT and e-Education. His focuses include the use of new ICT for Health Professional Training in Resource-Poor Countries; eLearning resources and systems. In CYSTINET-Africa (Mozambique), Dr. Momade Amisse Ali will serve as IT, supporting the project in mobile phone/tablet data collection technique, CYSTINET social media and Networking.
Silinto Francisco
IT Task Force
Silinto Francisco is Bachelor in Communication Science and MSC Candidate of Software Engineering. Since 2010, he works at Lurio University in Mozambique, in the Information and communication technology area. He has skills and experience in web design and development of small web applications, database and social media management. In the CYSTINET-Africa (Mozambique) project, as IT member, Silinto Francisco will give his contribution, supporting the project in mobile phone and tablet data collection technique, CYSTINET social media and Networking.